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Do not add a second PDE5 tablet on the same day as the 10/100 swallow
4 min readReviewed 21 August 2026. Updated
At a glance
Page typeNote
CountOne tablet 10/100
ReviewerCamille Rousseau, MD
U.S. sildenafil and tadalafil labels each write a once-per-day frequency.
01How the strip is counted
Do not combine a labelled PDE5 inhibitor with other PDE5 inhibitors or other ED therapies. The maximum recommended dosing frequency on the U.S. sildenafil label is once per day.
Sexual stimulation is required on the U.S. labels that write these milligrams separately.
02Once-per-day on the U.S. tadalafil label
The maximum recommended dosing frequency on the U.S. tadalafil label is once per day. Do not take a double dose of tadalafil to make up a missed dose. Do not split tadalafil tablets; the entire dose should be taken.
03Nitrate stop on each U.S. label
Sildenafil is contraindicated in patients using any form of organic nitrate, either regularly or intermittently. Tadalafil is contraindicated in patients using any form of organic nitrate, either regularly or intermittently.
How to cite this page - Vancouver style
Halo Medix Medicines Reference. Do not add a second PDE5 tablet on the same day as the 10/100 swallow [Internet]. Montreal: Halo Medix; 21 August 2026 [cited 2026 Aug 21]. Available from: https://halomedix.com/notes/sildalist-not-two-pills/
('Readers around Montreal asked whether Sildalist 10/100 means two tablets. ', 'Answers follow the U.S. labels for each molecule.')
Catherine Roy, Petite-Italie asks
Do I take two tablets when the carton says 10/100?
Reply from our reviewer
Do not combine a labelled PDE5 inhibitor with other PDE5 inhibitors or other ED therapies.
Samir Haddad, Laval-des-Rapides asks
Can I add a 50 mg sildenafil tablet later the same day?
Reply from our reviewer
The maximum recommended dosing frequency on the U.S. sildenafil label is once per day. Do not combine a labelled PDE5 inhibitor with other PDE5 inhibitors or other ED therapies. The maximum recommended dose of sildenafil is 100 mg. The recommended starting dose of sildenafil for most patients is 50 mg.
Élodie Martel, Côte-Saint-Luc asks
Can I split the 10/100 tablet to take half now?
Reply from our reviewer
Do not split tadalafil tablets; the entire dose should be taken. The U.S. tadalafil label writes that line for tadalafil tablets. Sexual stimulation is required on the U.S. labels that write these milligrams separately.
Pierre-Luc Bouchard, Anjou asks
Does a nitrate spray still stop the visit?
Reply from our reviewer
Sildenafil is contraindicated in patients using any form of organic nitrate, either regularly or intermittently. Tadalafil is contraindicated in patients using any form of organic nitrate, either regularly or intermittently. The maximum recommended dosing frequency on each U.S. label is once per day.
Isabelle El-Amin, Outremont asks
What frequency is written on the U.S. sildenafil label?
Reply from our reviewer
The maximum recommended dosing frequency on the U.S. sildenafil label is once per day. The maximum recommended dose of sildenafil is 100 mg. The recommended starting dose of sildenafil for most patients is 50 mg. VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. Do not add a second sildenafil tablet the same day.
Thomas Bélanger, Verdun asks
What frequency is written on the U.S. tadalafil label?
Reply from our reviewer
The maximum recommended dosing frequency on the U.S. tadalafil label is once per day. Do not take a double dose of tadalafil to make up a missed dose. The recommended starting dose of tadalafil for use as needed is 10 mg. Do not split tadalafil tablets; the entire dose should be taken. Sexual stimulation is needed on the U.S. tadalafil label.
Nadia Fortier, Ahuntsic asks
What storage line is written on the U.S. Cialis carton?
Reply from our reviewer
Store at 25 C (77 F); excursions permitted to 15 to 30 C (59 to 86 F). Keep out of reach of children. Read the Sildalist carton that arrived if the printed range differs. U.S. Viagra storage is also 25 C (77 F); excursions permitted to 15 to 30 C (59 to 86 F).
Yanick Côté, Longueuil asks
What half-lives sit on the two U.S. labels?
Reply from our reviewer
The mean terminal half-life of tadalafil is 17.5 hours in healthy subjects. After a dose, the maximum tadalafil concentration is reached between 30 minutes and 6 hours. The median time to maximum concentration is about 2 hours. The maximum recommended dosing frequency on the U.S. tadalafil label is once per day. Do not combine a labelled PDE5 inhibitor with other PDE5 inhibitors or other ED therapies.
Amélie El-Khatib, Plateau asks
What half-life is written on the U.S. sildenafil label?
Reply from our reviewer
Both sildenafil and the metabolite have terminal half lives of about 4 hours. The maximum recommended dose of sildenafil is 100 mg. The recommended starting dose of sildenafil for most patients is 50 mg. VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. Sexual stimulation is required. The maximum recommended dosing frequency is once per day.
